how to extract dmt DMT interacts with the 5-HT2A receptors within the brain. It’s thought that the activation of this receptor is the primary mechanism used by DMT to produce its hallucinogenic and introspective effects. This is the same mechanism used by other classical psychedelics, including LSD, psilocybin, and mescaline.
Early research led by Dr. Calvin Carhart Harris and his colleagues have discovered psychedelics like DMT are able to inhibit what’s known as the default mode network (DMN). This is a series of interconnected brain regions that function to maintain our grasp on reality and keep other regions of the brain in check. When we take DMT, the default mode network is temporarily inhibited, allowing other regions of the brain to interact that wouldn’t normally. The term used to describe this is “entropy,” — which was borrowed from the field of thermodynamics. how to extract dmt
Higher levels of entropy are associated with type II consciousness, more creativity, out-of-the-box thinking, and hallucinogenic episodes. Learn more about how long dmt last
Ways to Use DMT
There are plenty of ways of getting DMT into the body besides vaping it. The conventional method is to drink it in a traditional preparation of herbs such as ayahuasca, but you can also smoke it or snort it.
Here’s a quick breakdown of the methods of consuming DMT:
Ayahuasca is a mixture of two or more Amazonian plants. Taken on their own, neither plant is psychoactive, but in combination, provides a long-lasting DMT experience.
The first component is the ayahuasca vine (Banisteriopsis caapi). This vine is a rich source of harmala alkaloids. These alkaloids inhibit an enzyme in the body called monoamine oxidase (MAO). MAO is responsible for breaking down certain neurotransmitters in the body, including serotonin, dopamine, norepinephrine, and DMT.
The second component is a source of DMT. There are a few plants that can be used for this, but Mimosa pudica or Psychotria viridis are the most common.
Normally, when one consumes a plant rich in DMT, it’s immediately destroyed by MAO in the digestive tract — so there are no psychedelic effects. When an MAO inhibitor (like the ayahuasca vine) is included, it blocks this effect and allows the DMT to exert its effects on the body.
Ayahuasca is consumed in the form of tea, usually facilitated by a trained shaman. It’s been studied extensively and is respected for its effects on mental health, existential anxiety, depression, addiction, spiritual development, and much more.
Changa is often referred to as “smokeable ayahuasca.” It leverages the same sort of combination as ayahuasca, but is designed to be smoked rather than consumed as a tea. It’s capable of producing very similar effects as ayahuasca, but the total experience is much shorter.
Changa is the closest natural alternative to vaping DMT.
3. Psychedelic Toad Venom
A toad found in the United States and Mexico secretes a cocktail of psychedelic and poisonous substances in venom glands on its back. This is designed to be a deterrent for predators trying to eat the toad. It’s toxic in high doses. In lower doses, it’s profoundly psychedelic — owing to the high concentration of 5-MeO-DMT.
This toad has many names, including Sapo, Bufo toad, the Colorado River Toad, or the Sonoran Desert Toad.
Shamans living in the region use the venom of the road to occasion mystical experiences for the sake of healing or divination.
The toad venom is used by smoking or vaping it. This destroys a lot of the toxic elements in the compound while preserving most of the DMT.
4. Freebase DMT
Both N,N,DMT and 5-MeO-DMT are available in freebase forms as well. This comes as a fine white or brownish powder that can then be smoked or mixed with E-liquids to use in a vape.
The benefit of freebase DMT is that you have the opportunity to test it before you use it.
You can use the Ehrlich reagent to ensure it’s an indole alkaloid and then the Marquis or Mendelen reagent to differentiate DMT from other indole psychedelics (like LSD or psilocybin). The Mecke reagent can then be used to rule out the presence of opiates.
Pharmahuasca is the pharmaceutical version of changa or ayahuasca. It’s made by combining a pharmaceutical MAO inhibitor with freebase DMT.
This preparation is not recommended. Prescription MAO inhibitors can be very dangerous if used incorrectly. Based on pharmahuasca trip reports available on Reddit or other psychedelic communities, this mixture is often far less “healing” than any of the other forms of DMT. how to extract dmt